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The drug Kanesten (candles): instructions for use and analogues

Canesten (vaginal tablets) (Canesten)

1 tablet vaginal Kanesten 100 contains:

Clotrimazole - 100 mg.

1 vaginal tablet Kanesten 200 contains:

Clotrimazole - 200 mg.

1 vaginal tablet Kanesten 500 contains:

Clotrimazole - 500 mg.

Other components (regardless of dosage): calcium lactate (pentahydrate), crospovidone, microcrystalline cellulose, hypromellose, lactose monohydrate, lactic acid, magnesium stearate, colloidal anhydrous dioxide, corn starch.

pharmachologic effect

Kanesten - vaginal tablets with a pronounced antifungal effect. Kanesten contains an antifungal substance of the imidazole derivative group - clotrimazole. Kanesten disrupts the production of ergosterol, which leads to damage (functional and structural) of the cytoplasmic membrane of fungi.

Clotrimazole is active against most yeasts and molds, as well as dermatophytes.

The fungicidal concentration of clotrimazole is up to 8.0 μg / ml. The fungicidal or fungistatic activity of clotrimazole depends on the concentration of the active substance at the site of infection.

In vitro, the pronounced activity of clotrimazole is manifested only in relation to mature fungi and proliferating elements, while the spores are usually limited to the sensitive drug Kanesten.

In addition to the antifungal activity, clotrimazole also exhibits activity against individual gram-positive microorganisms, trichomonads, as well as some strains of Gardnerella vaginalis (effective concentration of clotrimazole from 10 μg / ml (for bacteria) to 100 μg / ml (for trichomonads)).

Initially resistant to clotrimazole strains are rare, secondary resistance may develop, but is also quite rare.

During the study of clotrimazole, toxic and genotoxic effects were not observed, as well as negative effects on reproduction.

After vaginal application of clotrimazole in the form of tablets, systemic absorption did not exceed 10%. Once in the systemic circulation, clotrimazole is rapidly metabolized to inactive derivatives and excreted from the body. When using Canesten 500 vaginal tablets, plasma clotrimazole concentrations did not reach the minimum detection limit (the level was less than 10 ng / ml). When using clotrimazole intravaginal systemic effect is considered negligible.

Indications for use

Kanesten in the form of vaginal tablets is prescribed as a means of local therapy for infections of the genital tract (including vaginitis), which are associated with Candida fungi or other sensitive microorganisms. In particular, Kanesten can be used in the development of superinfection (including on the background of antibiotic therapy) caused by bacteria that are sensitive to clotrimazole.

Mode of application

Kanesten tablets are intended solely for intravaginal use. Oral pills are contraindicated! After using the drug, wash your hands thoroughly to prevent accidental clotrimazole in the eyes.

Vaginal tablets must be inserted deep into the vagina, preferably at bedtime. If the use of the applicator is not prohibited, the tablet is administered with its help, the most convenient is the introduction of the tablet in a supine position.

Vaginal tablets usually dissolve completely in the vagina, otherwise fragments of tablets come out of the vagina (in this case it is recommended to consider replacing vaginal tablets with another form of the drug).

Usually it is recommended to use 1 vaginal tablet at night.

The course of treatment depends on the chosen treatment regimen:

  • When using Kanesten 100 tablets, the course of treatment lasts 6 days.
  • When using Kanesten 200 tablets, the course of treatment lasts 3 days.
  • When using Kanesten 500 tablets, the treatment lasts 1 day.

Features of Kanesten application:

It is necessary to consult a doctor in case of:

  • The occurrence of the first signs of the disease (for accurate diagnosis and prescription of treatment).
  • If symptoms of the disease persist for more than 7 days after the start of therapy.
  • If symptoms of the disease reappear within 2 months.
  • If there is a rise in temperature (more than 38 degrees), nausea, pain in the back and lower abdomen, vaginal bleeding, vaginal purulent discharge, which have an unpleasant smell.

During therapy, it is necessary to stop sex life and undergo treatment together with a partner, in order to prevent reinfection and recurrence of the disease. The drug can reduce the effectiveness of latex contraceptives (including diaphragms and condoms).

If there is a simultaneous lesion of the vagina and external genital organs, it is desirable to prescribe a combination therapy with vaginal tablets and external agents.

At the time of menstruation, therapy with vaginal tablets is stopped, after the end of menstruation, the treatment should be resumed. During treatment should not be douching, as well as the use of tampons or drugs for intravaginal use.

Side effects

When using Kanesten intravaginal tablets, allergic reactions can develop (in the form of weakness, shortness of breath and urticaria), as well as reactions from the reproductive system (in the form of burning, discomfort, itching, swelling and hyperemia of the vagina and external genital organs).

In rare cases, during the course of therapy with Kanesten, abdominal pain may develop.


The studies did not reveal the effect of clotrimazole on the fetus, but the use of the drug during pregnancy is possible only under the strict supervision of a physician. During pregnancy, the use of vaginal tablets without an applicator is recommended.

In case of detection of a susceptible pathogen in late pregnancy, Kanesten can be used for the rehabilitation of the birth canal (in a dose of 100 mg in 1 vaginal tablet).

Release form

Vaginal tablets Kanesten 100 in blister packs of foil of 6 pieces, in a pack of 1 blister and applicator for intravaginal administration.

Vaginal tablets Kanesten 200 in blister packs of foil for 3 pieces, in a pack of 1 blister and applicator for intravaginal administration.

Vaginal tablets Kanesten 500 in blister packs of foil for 1 piece, in a pack of 1 blister and applicator for intravaginal administration.

Means "Kanesten" (candles)

Instructions for use reports that the drug is antifungal and antibacterial agent. It has a destructive effect on almost all microorganisms. After the introduction of the drug inhibited cell synthesis. It is because of this that growth of fungi is inhibited, and subsequently blocked altogether.

"Kanesten" causes the death of pathological cells. Resistance to it occurs quite rarely. The main active ingredient of the drug is clotrimazole.

Restrictions on use

Like other drugs, this drug has its own contraindications. When can not use "Kanesten" (candles)? The instruction says the following points:

  • in case of hypersensitivity to the main active ingredient of the drug,
  • period of menstruation or any bleeding of unknown etiology,
  • first three months of pregnancy.

Sometimes the list of restrictions may expand. That is why you should not use the medicine yourself. Consult your doctor for recommendations.

special instructions

As you know, the medicine can not be used while carrying a child. However, in some cases, gynecologists still prescribe this drug. In this case, you should always consider the risk to the child and the benefits of treatment for the expectant mother.

The drug is often prescribed in conjunction with additional drugs. However, it must be remembered that it can reduce the effects of certain antibacterial and antimicrobial agents.

Is it possible to replace the medicine with something?

You already know how the drug Kanesten (candles) has instructions. Analogues of the drug - this is a drug with a similar effect or the same composition. These include the following means:

When choosing an analogue, you should first consult with your doctor. Remember that other medicines may contain additional active ingredients. Also for them provides a completely different treatment regimen. Consider all contraindications and possible adverse reactions to the drug.


You have learned a lot about the drug "Canesten" (candles). Instructions, photos of the drug are presented in this article. Before use, always study the annotation. This will help you avoid adverse reactions and some of the consequences of inappropriate use. The drug also has other forms: cream, spray, solution. Instructions for their use is somewhat different from that described above.

Application spectrum

Canesten is a strong antifungal drug based on clotrimazole, which, in turn, is an imidazole derivative. This substance has a wide spectrum of action on various fungal formations. Due to the effectiveness and relative safety of clotrimazole, preparations based on it are widely used in modern practice. Such high popularity is due to the positive impact in the presence of the following categories of fungal formations:

These types of fungal infections are the causes of the formation of most of the afflictions of a corresponding nature. At the same time, the positive dynamics of Kanesten in relation to such infections causes its rather wide application. Based on this, it is possible to distinguish a list of diseases that can be treated with this tool:

  • lichen colored,
  • Candida lesions
  • dermatophytosis
  • Erythrasma
  • vulvitis
  • balanitis
  • vaginitis

This list of diseases allows you to understand how effective Kanesten and its analogues, based on clotrimazole, are. The effectiveness of this tool speaks for itself. The use of the drug in the complex therapy can give a positive result in the shortest possible time. At the same time, clotrimase-containing drugs, and in particular Kanesten, show the best results in the treatment of thrush.

Indications and contraindications

To perform the procedures aimed at eliminating the effects of candidiasis, used candles or vaginal tablets.

Instructions for use of the drug in this case is quite simple. Kanesten is inserted into the vagina by mechanical means 1 time per day for the night. At the same time, the time of application depends on the intensity of the lesion of the mucous membranes and its depth. The initial stages of the disease imply a fairly quick and simple treatment, while the advanced stages of the disease require long-term use of the drug in combination with other methods.

Despite the relative safety of the drug Kanesten, the instruction provides a list of contraindications, in the presence of which it is necessary to limit the use of the drug:

  • hypersensitivity to components
  • the presence of menstruation,
  • first trimester of pregnancy
  • lactation period.

The presence of the above conditions is the reason for the abolition of the drug. In this case, his very appointment should be made only by a specialist, observing a woman. It is he who determines the rules for taking the drug and the intensity of therapy. This is done on the basis of the clinical picture of the disease, observations and analyzes taken from the woman. Thus, the vaginal localization of candidiasis implies suppositories or tablets, while the spread of infection on the external skin requires the use of other forms of the drug, such as an ointment or cream. The latter are applied in a thin layer on the affected areas. At the same time, healthy skin should not be affected in order to avoid further spread of the infection to it.

Therapy and side effects

Kanesten itself is easily tolerated by the body. However, in some cases, there are some side effects due to the individual characteristics of the organism. They look like this:

  • irritation of the mucous membranes of the vagina,
  • itch
  • puffiness
  • burning,
  • appearances of specific secretions.

The presence of the above symptoms indicates the intolerance of the components of the drug and their rejection by the body. A similar situation and the detection of at least one of these signs is a kind of signal, and also requires immediate notification of the doctor and replacement of the drug with other similar means. At the same time, similar symptoms can be observed in both women and men undergoing therapy.

The treatment of vaginal candidiasis should be considered separately. It implies not only getting the woman out of the symptoms of the disease, but also carrying out similar activities in relation to the man. Such an approach is a necessity, since the man most likely is also a carrier of the infection. This statement applies only to the permanent sexual partner who is most at risk. As a rule, for the implementation of this direction of treatment using a cream or ointment that has a local effect. Therefore, it should be remembered that the treatment of thrush is an important activity that requires a responsible approach. This is the only way to ensure the recovery of both the woman and her sexual partner, as well as to guarantee their full recovery from the effects of the disease.


Kanesten is contraindicated in case of hypersensitivity to the drug.

Vaginal tablets, in addition, should not be used during menstruation.

Negative effect of clotrimazole on the fetus was not detected. However, during pregnancy, Kanesten can only be used under strict medical supervision.

Whether clotrimazole penetrates into breast milk has not been reliably established, therefore during lactation the drug can be used strictly as prescribed by a doctor.

Drug interaction

With the combined use of Kanesten with polyene antibiotics (nystatin, natamycin, amphotericin B), there is a mutual decrease in the effectiveness of the drugs.

The intravaginal form of clotrimazole can increase the plasma concentration of tacrolimus, taken orally, therefore it is necessary to control its content in serum.

Side effects

Candles Canesten and other forms of this drug are usually easily tolerated by patients. If used improperly, you may experience itching, burning, swelling, redness, small rashes at the treatment site. Instructions for use Kanesten says that people who do not tolerate clotrimazole may experience nausea, vomiting, abdominal pain and dizziness.

Applications during pregnancy and lactation

Kanesten - a drug that is not recommended for use during pregnancy and breastfeeding. It is actively absorbed into the bloodstream, passes through the placenta and enters the body of the child. May cause a delay in the development of nerve fibers.

All dosage forms of Kanesten have a fairly large list of analogues. You can replace this ointment with Clotrimazole, Amiklon, Candide, Canison, or Candibenem. The composition of the candles are similar Imidil and Canison. Spray Kanesten direct has no analogues.

Cost Kanesten depends on the dosage form and country of origin. You can buy the ointment for 70-130 rubles, vaginal suppositories - for 190-370, spray - 300-700. The price of the tool of domestic production is minimal.

Forms of release and composition

Canesten is available as a cream, spray and vaginal tablets.

Canesten is a drug based on clotrimazole. This active ingredient is a first-line drug of choice for diseases triggered by Candida yeast.

The drug Kanesten comes in three forms:

The cream is intended for the treatment of skin infections. It consists of clotrimazole (1 g - 0.01 g of the active substance), alcohols, water, polysorbate. The cream is available in tubes of 20 g.

Kanesten vaginal tablets and suppositories are available in two dosages - 100 and 500 mg of clotrimazole in one suppository (tablet). Auxiliary and formative components in the composition:

  • lactic acid,
  • lactose,
  • calcium lactate
  • starch,
  • shell components.

The drug in high dosage (500 mg) is available in packs of one vaginal tablet. Means in a smaller dosage (100 mg) comes in 6 tablets per carton. Each package contains applicators for convenient injection of medication into the vagina.

The spray contains 1 g of clotrimazole in 100 g (1% solution) and excipients. It is available in vials of 30 ml.

Clotrimazole-based products can be purchased at a pharmacy without a prescription. They differ in democratic cost and a large number of analogs, which greatly facilitates the treatment.

Features of the use of vaginal tablets

When using vaginal tablets should observe the following precautions:

  • do not use during menstruation,
  • refuse intimacy during treatment,
  • when spreading the infection to the labia, use cream additionally,
  • use only intravaginally, avoid swallowing or getting in eyes,
  • Do not use simultaneously with tampons, douching or spermicides.

Along with the treatment of a woman, it is necessary to treat her sexual partner. For this you can use cream Kanesten.


Abdominal pain signals an overdose

Kanesten solution does not cause acute intoxication, since it does not have a systemic effect on the body. Cream Kanesten, used according to the instructions for use, also can not cause an overdose.

Overdose is possible only if the drug is accidentally swallowed, ointment, spray or vaginal tablets Kanesten. In this case, there is severe pain in the epigastric region, nausea, dizziness, low blood pressure.

Instructions for use

Instructions for use of the drug Canesten gives the following scheme of use, depending on the dosage form:

  • suppositories: one deep in the vagina at bedtime,
  • ointment: apply to the affected skin and mucous membranes 1-2 times a day,
  • Kanesten spray: spray on the affected areas twice a day.

The duration of suppository use depends on the severity of the symptoms. In some cases, a single dose of the drug (500 mg) is used. In chronic candidiasis, treatment with tablets of 100 mg for 6 days is indicated. Before the introduction of the drug should be held under water for 20 seconds. Then the tablet is inserted into the applicator and is inserted deep into the vagina with its help.

For candidal balanitis or vulvitis ointment is used for 10 days. Dermatomycosis is treated for 4 weeks, lichen-colored lichen - 10-20 days, depending on the severity of symptoms.

Spray used in the same way, but after the disappearance of the symptoms of the disease, it is recommended to spray the agent on the skin for another 10 days to avoid recurrence of the disease.

Cost and analogues

Clotrimazole - a cheaper analogue of the drug

Kanesten can not boast of an affordable price. One vaginal tablet at a dosage of 500 mg costs about 400 rubles. Packaging with six tablets will cost about 500 rubles. The cost of spray and cream is about 400 rubles. The drug is available without a prescription, but rarely found in pharmacies.

In the absence of the drug in pharmacies can be used analogs of Canesten, pick them up is not difficult. A list of substitutes and analogues of the drug Kanesten is given in the table indicating the average cost and volume of packaging.