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Radoter from alcoholism - effective tablets for subcutaneous implantation

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All drugs for the treatment of alcohol dependence are divided into two main groups, differing in the principle of action: relieving the symptoms of voluntary suppression of craving for alcohol. An injection of alcoholism with Radother helps in the process of developing a negative reaction of the body to alcohol.

Consequences after the injection with Radother expressed in the following manifestations:

  • weakness,
  • hot flashes
  • regular nausea and vomiting,
  • heartbeat failure
  • lowering blood pressure.
When using Radotera, even a small proportion of ethyl alcohol causes real torment in the patient and this is what leads to the formation of aversion and rejection of alcohol. Medication treatment of alcoholism is a simple solution to a complex problem.

Contraindications Radothera

This drug has a number of serious contraindications:

  • severe stages of diseases of the cardiovascular system,
  • mental disorders
  • hepatitis,
  • severe traumatic brain injury.

It is worth noting a number of relative contraindications to receive Radotera:

  • the age of the patient is over 60,
  • residual manifestations of blood circulation disorders

When taking a dose of alcohol, the following effects from Radothera may occur:

  • heartbeat failure
  • blood in the urine
  • vomiting
  • lowering blood pressure
  • fainting.

Reviews of the drug indicate a high efficiency of use of the drug, and narcologists regularly use it for the treatment of alcohol dependence.

Radother drug

Radoter is a well-known medicine for the treatment of chronic alcoholism. The drug has also known analogues, which are used exclusively in drug treatment clinics, under the supervision of doctors. For example, before one of the leading "ingredients" Radoter was part of the drug Torpedo, hence the popular nickname for all drugs of this type).

The anti-alcohol medication is based on the chemical compound disulfiram, it is sometimes used in rehabilitation clinics and under its direct name. Today, there are more than 10 medicines on the antialcoholic medical market, the main component of which (or one of the main ones) is disulfiram. All of them work on the same principle, the method of application is the same.

Radoter is produced in two forms:

  • classic tablets for oral use
  • implantation tablets that are sutured by an alcoholic patient under the skin.

Indications for use

Radoter is included in the group of drugs called “Means for the correction of disorders in alcoholism, toxic and drug addiction”. Since today there is no reliable and one hundred percent remedy to get rid of alcohol addiction, all existing drugs are designed to “correct” the disease.

Indications for use of Radotera depend on one factor - the dosage form of the anti-alcohol agent. Tablets for internal use help to avoid disruptions (relapses) during the traditional treatment of addiction, that is, they are a full-fledged part of a comprehensive anti-alcohol therapy.

Radoter for subcutaneous implantation is used as the main tool for the treatment of chronic alcoholism. Also capsules for "stitching" can be used in chronic nickel poisoning, for detoxification.

Mechanism of action

All means for the correction of health problems in alcoholism are divided into 2 large groups according to the principle of action. This is the withdrawal of withdrawal symptoms or the formation of aversion to ethyl alcohol. Specifically, the drug Radoter (like other drugs based on disulfiram) produces a sharply negative reaction of the body to alcohol poison - at the level of reflexes.

The alcoholic immediately feels this on himself, instantly appearing:

  • general malaise,
  • hot flashes (hot flashes when the face turns red and breaks sweat)
  • repeated nausea and vomiting,
  • tachycardia,
  • pressure drops rapidly.

If a person drinks a course of Radothera tablets or suffered an injection, even the slightest "ethyl dose" will bring real torment. Due to this effect, the rejection of alcohol should be formed. Even a chronic alcoholic after one or two such attacks will no longer take the next glass / glass as a pleasure, a pleasant pastime, or even vital dope.

Instructions for use

Instructions for the use of anti-alcohol drugs Radoter entirely depends on the form of release:

  • If these are traditional tablets for internal use, then it is necessary to swallow them in the morning, on an empty stomach. After a dose of medication, a full breakfast should certainly follow. Mandatory dose at the beginning of therapy - 500 mg / day. By the end of the course of treatment, 250-125 mg / day is gradually reduced.

The validity period of one oral dose of Radothera is 48 hours. The decision on the duration of treatment and dosage is made solely by a narcologist - based on the tests, the patient's condition and the stage of alcohol dependence.

  • The standard dosage of tablets for implantation is 8 pieces of 100 gr. Sew them in the left ileum area, at a low level, so that the patient does not rub the incision area with a belt. Carefully make 4 incisions and insert 2 tablets each into the subcutaneous tissue, to a depth of 4 cm. Then, a regular suture and a sterile dressing are applied.

Usually the first implantation is done for a short time. If the patient tolerates the treatment easily and calmly abstains from alcohol for the indicated period, the doctor may decide to re-inject. In this case, the dates are already increasing.

In addition, the validity of the injection intravenously long enough, and after extraction - 5-9 months. This is because when sewed in, disulfiram slowly begins to be absorbed into the blood, and by the time it is “decoding” it reaches a rather high concentration.

Side effects

In the treatment of Radoterom, side effects are not excluded.

When using tablets for oral administration can occur such violations:

  • unpleasant metallic taste in the mouth,
  • liver damage (hepatitis),
  • neuropsychiatric disorders
  • memory problems
  • headaches,
  • disorientation in time and space
  • general weakness
  • allergic skin reactions
  • leg polyneuropathy (sensitivity disorders, partial paralysis, etc.).

After implanting Radoter tablets, the following complications are recorded:

  • suppuration of the place where the implant was inserted (due to friction, early removal of sutures),
  • rejection reaction (if pills are not deeply injected),
  • allergic reaction.

If during the treatment to take a dose of alcohol, it can cause the following consequences:

  • heart rhythm disorders
  • swelling of the brain
  • myocardial infarction,
  • hemorrhagic stroke,
  • collapse (a life-threatening condition in which pressure drops sharply and the functioning of all vital organs is disrupted).

Reviews of patients and physicians say that after taking the drug, the addict is fully aware of all the “charm” of alcohol intoxication. Nausea, vomiting, severe malaise - this is what helps to form an aversion to alcoholic beverages and get rid of pernicious addiction.

pharmachologic effect

Antialcoholic. Inhibits acetaldehyde dehydrogenase and inhibits the enzymatic biotransformation of alcohol at the stage of acetic aldehyde. The accumulation of the latter in the body causes intoxication, which (since consciousness is preserved) is accompanied by heavy sensations. Quickly and completely absorbed in the digestive tract. It is extensively metabolized, recovering to diethyldithiocarbonate, excreted by the kidneys as a glucuronide, or it decomposes to form diethylamine and carbon disulfide, which is secreted by the lungs.

When not to apply

Hypersensitivity, thyrotoxicosis, diabetes mellitus, pronounced cardiosclerosis, cerebral arteriosclerosis, pre-and post-infarction conditions, aortic aneurysm, coronary insufficiency, hypertensive disease of the II-III stages, cardiovascular diseases in the decompensation stage, pulmonary tuberculosis of the II-III stages, cardiovascular diseases in the decompensation stage, pulmonary tuberculosis of the II-III stages, cardiovascular diseases in the decompensation stage, pulmonary tuberculosis, stage II-III, cardiovascular diseases in the decompensation stage, pulmonary tuberculosis, heart disease in a decommissioned disease , severe emphysema, erosion of the stomach, liver and kidney disease, mental illness, epileptiform syndrome, polyneuritis, glaucoma, pregnancy. Limitations to use: age older than 60 years, gastric ulcer and duodenal ulcer (in acute stage), endarteritis, previously transferred psychosis in patients receiving disulfiram.

Contraindications for use

Hypersensitivity, thyrotoxicosis, diabetes mellitus, pronounced cardiosclerosis, cerebral arteriosclerosis, pre-and post-infarction conditions, aortic aneurysm, coronary insufficiency, hypertensive disease of the II-III stages, cardiovascular diseases in the decompensation stage, pulmonary tuberculosis of the II-III stages, cardiovascular diseases in the decompensation stage, pulmonary tuberculosis of the II-III stages, cardiovascular diseases in the decompensation stage, pulmonary tuberculosis, stage II-III, cardiovascular diseases in the decompensation stage, pulmonary tuberculosis, heart disease in a decommissioned disease , severe emphysema, erosion of the stomach, liver and kidney disease, mental illness, epileptiform syndrome, polyneuritis, glaucoma, pregnancy. Limitations to use: age older than 60 years, gastric ulcer and duodenal ulcer (in acute stage), endarteritis, previously transferred psychosis in patients receiving disulfiram.

Pharmacological properties

Antialcoholic. Inhibits acetaldehyde dehydrogenase and inhibits the enzymatic biotransformation of alcohol at the stage of acetic aldehyde. The accumulation of the latter in the body causes intoxication, which (since consciousness is preserved) is accompanied by heavy sensations. Quickly and completely absorbed in the digestive tract. It is extensively metabolized, recovering to diethyldithiocarbonate, excreted by the kidneys as a glucuronide, or it decomposes to form diethylamine and carbon disulfide, which is secreted by the lungs.

Cautions when using

Before implantation, a course of gradual weaning of the patient from ethanol should be performed. Polyneuropathy, which occurs when using the drug, disappears when prescribing B vitamins or removing implanted tablets. At the site of implantation, a small bump is often formed, due to fibrosis of the skin and subcutaneous fat. In the case of simultaneous administration with oral anticoagulants, it is necessary to carry out more frequent monitoring of the prothrombin content and dose adjustment of anticoagulants, which is associated with an increased risk of bleeding.

Interaction with drugs

Effects (including neurotoxic) enhance tricyclic antidepressants (amitriptyline), metronidazole, isoniazid, reduces ascorbic acid (reaction to ethanol). Increases plasma concentration of drugs metabolized in the liver due to inhibition of microsomal oxidation. Enhances the toxic effects of antipyrine, phenytoin, chlordiazepoxide and diazepam by inhibiting their metabolism. Isoniazid increases the risk of behavioral disturbances and coordination of movements. Phenytoin increases the risk of side effects, metronidazole - the risk of mental disorders, the occurrence of delusions. Enhances the effect of indirect anticoagulants and increases the risk of bleeding.

Dosage and Administration Radoter

Tablets: by mouth, on an empty stomach in the morning, before breakfast, at the beginning of treatment the average dose is 500 mg / day, then it is gradually reduced to 250-125 mg / day. P / to and / m (implantation). After thorough disinfection and local anesthesia, a small incision (approximately 6 mm) is made in the left iliac region, low enough to avoid friction with the belt. The subcutaneous tissue is pushed apart and using a trocar, 2 tablets are introduced for implantation (100 mg each) to a depth of 4 cm. This procedure is repeated 4 times, injecting tablets crosswise around the incision site, parallel to the skin surface. The total dose is 800 mg (8 tablets). The incision is stitched, followed by a sterile dressing.

Content

Regular drinking of strong drinks is so firmly rooted in our lives that many consider this phenomenon to be normal, in the order of things, but not a harmful habit. Although chronic alcoholism is not so easy to get rid of. Treatment takes more than one year, and sometimes several decades. To pull the closest person out of this "swamp" is not limited to pharmacy drugs. Relatives turn for help to traditional medicine, do not shun advertised “fashionable” supereffective medicines. The drug Radoter from alcoholism is often used in medical centers.

During the course of treatment, it is important that the patient does not “fail”, i.e. there was no rollback to the former way of life.

It remains to rely on your intuition, so as not to be mistaken with the choice of the best anti-alcohol method. This article deals with coding or the so-called “torpedoes”, which help to overcome alcohol dependence.

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